Also reassuring Only five human clinical as opposed to just preclinical in vitro or in vivo recently published pharmacokinetic drug clinical interaction studies Battu 2008 Gurley 2008 MoltГі 2011 MoltГі 2012 Penzak 2010 have fully determined the influence of chemically characterized Echinacea preparations on CYP3A4 and CYP2D6 in humans all previous studies were of uncharacterized Echinacea extracts, so it is impossible to determine components and their influence
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